MAIN CONTRIBUTIONS OF ENZYME-PRODUCING BACTERIA WITH THERAPEUTIC AND COSMETIC APPLICATIONS: AN INTEGRATIVE LITERATURE REVIEW
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Abstract
Bacteria, traditionally associated with pathological processes, also present significant biotechnological potential, particularly in the production of enzymes with therapeutic and cosmetic applications. Advances in biotechnology and genetic engineering have enabled the safe and efficient use of these microorganisms as sustainable sources of bioactive compounds. In this context, the present study aimed to analyze the main contributions of enzyme-producing bacteria for therapeutic and cosmetic use through an integrative literature review. Searches were conducted in the SciELO, Google Scholar, and PubMed databases using descriptors related to bacteria, microorganisms, cosmetics, and medicines, including publications from 2018 to 2023. After applying inclusion and exclusion criteria, six studies were selected for analysis. The results demonstrate that bacteria are capable of producing high-quality enzymes, such as proteases, amylases, lipases, nucleases, and catalases, which are widely used in therapeutic treatments and cosmetic formulations. The use of bacterial cellulose combined with natural compounds, such as propolis extract, and the application of non-thermal plasma to improve cosmetic properties were also highlighted. It is concluded that bacteria represent an efficient, sustainable, and cost-effective alternative for enzyme production, significantly contributing to the development of innovative therapeutic and cosmetic products, provided that strict safety and quality control measures are applied.
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